GABRA4
Gamma-aminobutyric acid (GABA) activates at GABA-A receptors, which are ligand-gated chloride channels, and is the main inhibitory neurotransmitter in the mammalian brain. These channels' chloride conductance can be altered by substances like benzodiazepines that attach to the GABA-A receptor. GABA-A receptors have at least 16 different subunits that have been discovered. This gene encodes subunit alpha-4, which interacts with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1), to ultimately raise the risk of autism. Subunit alpha-4 is involved in the etiology of autism.
| Full Name | Gamma-aminobutyric acid type A receptor subunit alpha4 |
| Gene ID | Human: 2557 Mouse: 14397 Rat: 140675 Monkey: 704008 |
| UniProt ID | Human: P48169 Mouse: Q9D6F4 Rat: P28471 Monkey: F6YLN4 |
| Alternative Names | Gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor, alpha 4; gamma-aminobutyric acid (GABA) A receptor, alpha 4; gamma-aminobutyric acid A receptor alpha 4; gamma-aminobutyric acid type A receptor alpha4 subunit; GABRA4; Gamma-aminobutyric acid type A receptor subunit alpha4 |
Product List
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Magic™ mPro Human GABAA4/α4β3γ2 Cell Line
[CAT#: S01YF-1122-KX83]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GABAA4/α4β3γ2 Target Family: Ligand Gated Ion Channel; GABAA Assay Target Protein Species: Human
mProX™ Human GABRA4 Stable Cell Line
[CAT#: S01YF-1123-KX67]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GABRA4 Target Family: GABAA Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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