FLT3
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
| Full Name | fms related receptor tyrosine kinase 3 |
| Gene ID | Human: 2322 Mouse: 14255 Rat: 140635 Monkey: 721712 |
| UniProt ID | Human: P36888 Mouse: Q00342 Rat: A0A0G2JW59 |
| Alternative Names | FLK2; STK1; CD135; FLK-2;receptor-type tyrosine-protein kinase FLT3;CD135 antigen;FL cytokine receptor;fetal liver kinase 2;fms related tyrosine kinase 3;fms-like tyrosine kinase 3;growth factor receptor tyrosine kinase type III;stem cell tyrosine kinase 1 |
Product List
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Magic™ Human FLT3 & ITD & AXL BaF3 Cell Line
[CAT#: S01YF-1222-KX832]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 & ITD & AXL Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (D835V) BaF3 Cell Line
[CAT#: S01YF-1222-KX823]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (D835V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (D835Y) BaF3 Cell Line
[CAT#: S01YF-1222-KX830]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (D835Y) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate) BaF3 Cell Line
[CAT#: S01YF-1222-KX843]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, A848P) BaF3 Cell Line
[CAT#: S01YF-1222-KX797]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, A848P) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, D835Del) BaF3 Cell Line
[CAT#: S01YF-1222-KX796]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D835Del) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, D835F) BaF3 Cell Line
[CAT#: S01YF-1222-KX795]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D835F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, D835H) BaF3 Cell Line
[CAT#: S01YF-1222-KX794]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D835H) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 BaF3 Cell Line
[CAT#: S01YF-1222-KX844]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
mProX™ Human FLT3 Stable Cell Line
[CAT#: S01YF-1123-KX243]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: AML; CHO-K1; HEK293
Magic™ Human FLT3 (ITD duplicate, D835I) BaF3 Cell Line
[CAT#: S01YF-1222-KX793]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D835I) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, D835V) BaF3 Cell Line
[CAT#: S01YF-1222-KX822]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D835V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, D835Y) BaF3 Cell Line
[CAT#: S01YF-1222-KX829]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D835Y) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, D849G) BaF3 Cell Line
[CAT#: S01YF-1222-KX792]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, D849G) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, F691I) BaF3 Cell Line
[CAT#: S01YF-1222-KX780]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, F691I) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, N767D) BaF3 Cell Line
[CAT#: S01YF-1222-KX791]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, N767D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, Y842C) BaF3 Cell Line
[CAT#: S01YF-1222-KX790]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, Y842C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FLT3 (ITD duplicate, Y842H) BaF3 Cell Line
[CAT#: S01YF-1222-KX789]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FLT3 (ITD duplicate, Y842H) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
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