mProX™ Human FLT3 Stable Cell Line
[CAT#: S01YF-1123-KX243]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
FLT3
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
AML; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research
Related Diseases
Leukemia, Acute Myeloid and Acute Myeloblastic Leukemia Without Maturation. Among its related pathways are sorafenib-resistant FLT3 mutants and GPCR Pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Fms-like tyrosine kinase 3 (FLT3), a member of the receptor tyrosine kinase (RTK) protein family, is encoded by the FLT3 gene. A process known as signal transduction is used by receptor tyrosine kinases to transfer messages from the cell surface within the cell. Certain cell types include the FLT3 protein on their outer membrane, where it can attach to a particular protein known as FLT3 ligand, or FL. The FLT3 protein is activated by this interaction, and this in turn activates a number of intracellular proteins that are involved in several signaling cascades. The FLT3 protein stimulates signaling pathways that regulate numerous critical physiological functions, including cell growth, division, and survival, especially those of hematopoietic progenitor cells, which are precursors to blood cells. The customized FLT3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Deborah
This FLT3 cell line enabled us to conduct our experiments with confidence, and we achieved publication-worthy data.
Sep 19 2021
Verified Customer
James
The FLT3 cell line demonstrated remarkable specificity and sensitivity, which helped us unravel complex signaling pathways.
Mar 18 2023
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
