FGFR4
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
| Full Name | fibroblast growth factor receptor 4 |
| Gene ID | Human: 2264 Mouse: 14186 Rat: 25114 Monkey: 698494 |
| UniProt ID | Human: P22455 Mouse: Q03142 Rat: Q498D6 |
| Alternative Names | TKF; JTK2; CD334;fibroblast growth factor receptor 4;hydroxyaryl-protein kinase;protein-tyrosine kinase;tyrosine kinase related to fibroblast growth factor receptor;tyrosylprotein kinase |
Product List
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Magic™ Human FGFR4 & ETV6 BaF3 Cell Line
[CAT#: S01YF-1222-KX611]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FGFR4 & ETV6 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human FGFR4 (N535K) BaF3 Cell Line
[CAT#: S01YF-1222-KX762]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FGFR4 (N535K) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
mProX™ Human FGFR4 Stable Cell Line
[CAT#: S01YF-1123-KX240]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FGFR4 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HUH7; HEP3B; HEPG2; CHO-K1; HEK293
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