mProX™ Human FGFR4 Stable Cell Line
[CAT#: S01YF-1123-KX240]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
FGFR4
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
HUH7; HEP3B; HEPG2; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research
Related Diseases
Rhabdomyosarcoma and Breast Cancer. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Downstream signaling of activated FGFR2
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
In humans, the FGFR4 gene encodes the protein known as fibroblast growth factor receptor 4. Another designation for FGFR4 is CD334. The fibroblast growth factor receptor family, whose members' amino acid sequences have been extensively conserved both among themselves and throughout evolution, includes the protein that this gene encodes. Members of the FGFR family exhibit variations in their tissue distribution and ligand affinity. A complete representative protein would have three immunoglobulin-like domains in its extracellular portion, one hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The protein's extracellular component interacts with growth factors for fibroblasts, initiating a series of downstream signals that ultimately affect mitogenesis and differentiation. The customized FGFR4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
William
This FGFR4 cell line is sensitive and specific. I definitely recommend this cell line.
Jul 28 2020
Verified Customer
Amanda
I must say that I am extremely impressed with its performance. The FGFR4 cell line was easy to use and provided excellent results in my experiments.
Jan 19 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
