F2RL1
A protein from the G-protein coupled receptor 1 family is encoded by this gene. The extracellular amino terminus of the encoded cell surface receptor is cleaved by proteases, which produces a new amino terminus that functions as a tethered ligand that binds to an extracellular loop domain. It has been demonstrated that activating the receptor causes blood vessels to widen, improves blood flow, and lowers blood pressure. Along with innate and adaptive immunity, this protein is crucial for the inflammatory response.
| Full Name | F2R like trypsin receptor 1 |
| Gene ID | Human: 2150 Mouse: 14063 Rat: 116677 Monkey: 707479 |
| UniProt ID | Human: P55085 Mouse: P55086 Rat: Q63645 Monkey: A0A2K6D3B8 |
| Alternative Names | PAR2; GPR11; proteinase-activated receptor 2; G-protein coupled receptor 11; coagulation factor II (thrombin) receptor-like 1; protease-activated receptor 2; thrombin receptor-like 1; F2RL1; F2R like trypsin receptor 1 |
Product List
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Magic™ Human F2RL1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX147]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human F2RL1 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX99]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-activated receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human F2RL1 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX113]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human FLAG tagged F2RL1 HeLa Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX558]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Assay Types: Calcium flux assay
Magic™ mPro Human F2RL1 Cell Line
[CAT#: S01YF-1122-KX51]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated Target Protein Species: Human
mProX™ Human F2RL1 Stable Cell Line
[CAT#: S01YF-0923-KX14]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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