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ESRRG

A member of the nuclear hormone receptor superfamily's estrogen receptor-related receptor (ESRR) family is encoded by this gene. A DNA binding domain made up of two C4-type zinc finger motifs is shared by all members of the ESRR family. The ESRR family members are orphan nuclear receptors that bind to the estrogen response element and the steroidogenic factor 1 response element and, in the absence of ligands, activate the genes regulated by both response elements. The estrogen receptor (ER) family and the ESRR family are closely linked. The ESRRs appear to interfere with the ER-mediated estrogen response in a variety of ways because they share target genes, co-regulators, and promoters.

Full Name Estrogen related receptor gamma
Gene ID Human: 2104
Mouse: 26381
Rat: 360896
Monkey: 106992350
UniProt ID Human: P62508
Mouse: P62509
Rat: P62510
Monkey: F7ALW0
Alternative Names ERR3; ERRg; NR3B3; ERRgamma; ERR-gamma; estrogen-related receptor gamma; ERR gamma-2; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3

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Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: ERRgamma Target Family: Estrogen-related Receptor Target Protein Species: Human Assay Types: Protein-Protein Interaction Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: ESRRG Target Family: Estrogen-related Receptor Target Protein Species: Human Host Cell Type: ESCC; CHO-K1; HEK293
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