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  • mProX™ Human ESRRG Stable Cell Line

    [CAT#: S01YF-1123-KX99]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Nuclear Receptor

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    Host Cell Type:
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    Product Information

    Target Protein
    ESRRG
    Target Family
    Estrogen-related Receptor
    Target Protein Species
    Human
    Host Cell Type
    ESCC; CHO-K1; HEK293
    Target Classification
    Nuclear Receptor
    Target Research Area
    Reproductive Research
    Related Diseases
    Usher Syndrome; Amelogenesis Imperfecta
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The ESRRG gene in humans encodes the nuclear receptor known as estrogen-related receptor gamma (ERR-gamma), or NR3B3. This protein belongs to the family of steroid hormone receptors known as nuclear hormone receptors. The orphan receptor lacks a physiological activating ligand; nonetheless, inverse agonists such as diethylstilbestrol and 4-hydroxytamoxifen deactivate ESRRG. Variations in bisphenol A effects could be explained by varying ERR-γ expression in different body areas. For example, observations of excessive bisphenol A accumulation in the placenta may be explained by the high quantity of ERR-γ detected there. The customized ESRRG stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Melissa

    Its user-friendly design have simplified the process of ESRRG drug discovery in our lab. Jul 11 2022

    chat Verified Customer

    chat David

    I have used the mouse ESRRG KD cell line extensively in my studies, and it consistently delivered outstanding performance. May 21 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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