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ESR2

A member of the nuclear receptor transcription factor superfamily and the estrogen receptor family is encoded by this gene. The gene product is found in the nucleus, cytoplasm, and mitochondria and has an N-terminal DNA binding domain and a C-terminal ligand binding domain. The encoded protein creates homo- or hetero-dimers that interact with particular DNA regions to induce transcription after binding to 17beta-estradiol or similar ligands. Other members of the estrogen receptor family's function are predominately inhibited by some isoforms.

Full Name Estrogen receptor 2
Gene ID Human: 2100
Mouse: 13983
Rat: 25149
Monkey: 574110
UniProt ID Human: Q92731
Mouse: O08537
Rat: Q62986
Monkey: Q9TTE5
Alternative Names Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA; estrogen receptor beta; estrogen receptor beta 2; estrogen receptor beta 4; nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta

Product List

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Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: ERbeta Target Family: Estrogen Receptor Target Protein Species: Human Assay Types: Protein-Protein Interaction Assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: ERbeta Target Family: Estrogen Receptor Target Protein Species: Human Assay Types: Radioligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: ESR2 Target Family: Estrogen Receptor Target Protein Species: Human Host Cell Type: FaDu; Cal27; CHO-K1; HEK293
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