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    mProX™ Human ESR2 Stable Cell Line

    [CAT#: S01YF-1123-KX96]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Nuclear Receptor

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    Product Information

    Target Protein
    ESR2
    Target Family
    Estrogen Receptor
    Target Protein Species
    Human
    Host Cell Type
    FaDu; Cal27; CHO-K1; HEK293
    Target Classification
    Nuclear Receptor
    Target Research Area
    Cancer Research; Reproductive Research
    Related Diseases
    Ovarian Dysgenesis; Thyroid Carcinoma
    Gene ID
    2100
    UniProt ID
    Q92731

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    NR3A2, or estrogen receptor beta (ERβ), is one of the two primary forms of estrogen receptors. The ESR2 gene encodes ERβ in humans. ERβ belongs to the nuclear receptor transcription factor superfamily as well as the family of estrogen receptors. The gene product is located in the cytoplasm, mitochondria, and nucleus. It has an N-terminal DNA binding domain and a C-terminal ligand binding domain. The encoded protein forms homo- or hetero-dimers with estrogen receptor α upon binding to 17-β-estradiol, estriol, or analogous ligands. These interactions with specific DNA sequences trigger transcription. The activity of other members of the estrogen receptor family is dominantly inhibited by certain isoforms. Strong tumor suppressor ERβ is involved in many cancer types, including prostate cancer and ovarian cancer. The customized ESR2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    There are currently no Customer reviews or questions for mProX™ Human ESR2 Stable Cell Line (S01YF-1123-KX96). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Rebecca (Verified Customer)

    What is the species for ESR2 cell line? Jul 10 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    We can customize the species you need, such as human, mouse. Jul 10 2022

    chat Donna (Verified Customer)

    What are other names for ESR2? Jul 24 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    This target may also be called "Est, ERbe, ER[b], Estrb, ERbeta" in publications. Jul 24 2023

    Related Products by Target
    • mProX™ Human ESR2 Stable Cell Line (CAT#: S01YF-1123-KX96)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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