EPHB4

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Full Name	EPH receptor B4
Gene ID	Human: 2050 Mouse: 13846 Rat: 686310 Monkey: 719320
UniProt ID	Human: P54760 Mouse: P54761 Rat: M0RDA4
Alternative Names	HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11;ephrin type-B receptor 4;ephrin receptor EphB4;hepatoma transmembrane kinase;tyrosine-protein kinase TYRO11;tyrosine-protein kinase receptor HTK

Product List

mProX™ Human EPHB4 Stable Cell Line [CAT#: S01YF-1123-KX235]

Product Category:: Membrane Protein Stable Cell Lines

Datasheet

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