mProX™ Human EPHB4 Stable Cell Line

[CAT#: S01YF-1123-KX235]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1133	Magic™ Human EPHB4 in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

EPHB4

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

CNS Research; Reproductive Research

Related Diseases

Capillary Malformation-Arteriovenous Malformation 2 and Lymphatic Malformation 7. Among its related pathways are GPCR Pathway and EPH-Ephrin signaling

Gene ID

2050

UniProt ID

P54760

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The human EPHB4 gene encodes the protein known as ephrin type-B receptor 4. Many developmental processes are mediated by ephrin receptors and their ligands, the ephrins, especially in the nervous system. Pherins can be classified into two groups based on their sequence connections and structures: the transmembrane ephrin-B (EFNB) class and the glycosylphosphatidylinositol-anchored ephrin-A (EFNA) class. Based on the similarity of their extracellular domain sequences and their propensity to bind ephrin-A and ephrin-B ligands, the Eph family of receptors is split into two categories. Within the receptor tyrosine kinase (RTK) family, ephrin receptors comprise the biggest subgroup. This gene codes for a protein that interacts to ephrin-B2 and is crucial for the creation of new blood vessels. The customized EPHB4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Cynthia

Reliable and repeatable throughout the EPHB4 cell line use. Jun 18 2021

chat Verified Customer

chat Timothy

I highly recommend the EPHB4 cell line for anyone working on membrane protein research. Jun 23 2020

chat Verified Customer

FAQ

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