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EPHB3

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.

Full Name EPH receptor B3
Gene ID Human: 2049 Mouse: 13845 Rat: 287989 Monkey: 701811
UniProt ID Human: P54753 Mouse: P54754 Rat: D3ZH39
Alternative Names EK2; ETK2; HEK2; TYRO6;ephrin type-B receptor 3;EPH-like tyrosine kinase 2;embryonic kinase 2;human embryo kinase 2;tyrosine-protein kinase TYRO6

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EPHB3 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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