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EPHB1

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Full Name EPH receptor B1
Gene ID Human: 2047 Mouse: 270190 Rat: 24338 Monkey: 717211
UniProt ID Human: P54762 Mouse: Q8CBF3 Rat: P09759
Alternative Names ELK; NET; Hek6; EPHT2;ephrin type-B receptor 1;EK6;EPH-like kinase 6;eph tyrosine kinase 2;neuronally-expressed EPH-related tyrosine kinase;tyrosine-protein kinase receptor EPH-2

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EPHB1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: U251; U87; CHO-K1; HEK293
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