EPHA8
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
| Full Name | EPH receptor A8 |
| Gene ID | Human: 2046 Mouse: 13842 Rat: 60589 Monkey: 708378 |
| UniProt ID | Human: P29322 Mouse: O09127 Rat: P29321 |
| Alternative Names | EEK; EK3; HEK3;ephrin type-A receptor 8;EPH- and ELK-related kinase;EPH- and ELK-related tyrosine kinase;EPH-like kinase 3;hydroxyaryl-protein kinase;protein-tyrosine kinase;tyrosine-protein kinase receptor EEK;tyrosylprotein kinase |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EPHA8 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: SCC-25; CHO-K1; HEK293
