EIF2AK2
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.
| Full Name | eukaryotic translation initiation factor 2 alpha kinase 2 |
| Gene ID | Human: 5610 Mouse: 19106 Rat: 54287 Monkey: 708912 |
| UniProt ID | Human: P19525 Mouse: Q03963 Rat: Q63184 |
| Alternative Names | PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83;interferon-induced, double-stranded RNA-activated protein kinase;P1/eIF-2A protein kinase;double stranded RNA activated protein kinase;eIF-2A protein kinase 2;interferon-inducible elF2alpha kinase;p68 kinase;protein kinase R;protein kinase RNA-regulated;protein kinase, interferon-inducible double stranded RNA dependent;protein phosphatase 1, regulatory subunit 83;tyrosine-protein kinase EIF2AK2 |
Product List
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mProX™ Human EIF2AK2 Stable Cell Line
[CAT#: S01YF-1023-PY76]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;PANC-1 Assay Types: Biological assays
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