EGFR
This gene produces a transmembrane glycoprotein, which belongs to the protein kinase superfamily. This protein functions as an epidermal growth factor receptor. The cell surface protein known as EGFR interacts with epidermal growth factor to cause receptor dimerization and tyrosine autophosphorylation, which promotes cell growth. Lung cancer is linked to mutations in this gene. A severe type of Coronavirus Disease 2019 (COVID-19) caused by infection with severe acute respiratory syndrome coronavirus-2 has EGFR as a contributing factor (SARS-CoV-2).
Full Name | Epidermal growth factor receptor |
Gene ID | Human: 1956 Mouse: 13649 Rat: 24329 Monkey: 613027 |
UniProt ID | Human: P00533 Mouse: Q01279 Rat: Q9WTS1 Monkey: P55245 |
Alternative Names | ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2; epidermal growth factor receptor; EGFR vIII; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & EGFR Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: EGFR Target Family: Kinases/Enzyme