EGFR
This gene produces a transmembrane glycoprotein, which belongs to the protein kinase superfamily. This protein functions as an epidermal growth factor receptor. The cell surface protein known as EGFR interacts with epidermal growth factor to cause receptor dimerization and tyrosine autophosphorylation, which promotes cell growth. Lung cancer is linked to mutations in this gene. A severe type of Coronavirus Disease 2019 (COVID-19) caused by infection with severe acute respiratory syndrome coronavirus-2 has EGFR as a contributing factor (SARS-CoV-2).
Full Name | Epidermal growth factor receptor |
Gene ID | Human: 1956 Mouse: 13649 Rat: 24329 Monkey: 613027 |
UniProt ID | Human: P00533 Mouse: Q01279 Rat: Q9WTS1 Monkey: P55245 |
Alternative Names | ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2; epidermal growth factor receptor; EGFR vIII; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & EGFR Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR & ERBB3 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A289D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A289T) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A289V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A763, Y764insFHEA) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A763, Y764insFQEA) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A763, Y764insFQEA, C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d752-759) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (D761Y) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (D770, N771insG) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (D770, N771insGF) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (D770, N771insGT) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (D770, N771insNPG) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, S768I) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, T790M) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, T790M, C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, T790M, L798I) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, T790M, L858R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d747-749) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d747-749, A750P) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A763, Y764insFQEA, T790M) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (A767, S768insTLA) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (C797A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, C797A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EGFR (d746-750, C797G) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay