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EGFR

This gene produces a transmembrane glycoprotein, which belongs to the protein kinase superfamily. This protein functions as an epidermal growth factor receptor. The cell surface protein known as EGFR interacts with epidermal growth factor to cause receptor dimerization and tyrosine autophosphorylation, which promotes cell growth. Lung cancer is linked to mutations in this gene. A severe type of Coronavirus Disease 2019 (COVID-19) caused by infection with severe acute respiratory syndrome coronavirus-2 has EGFR as a contributing factor (SARS-CoV-2).

Full Name Epidermal growth factor receptor
Gene ID Human: 1956
Mouse: 13649
Rat: 24329
Monkey: 613027
UniProt ID Human: P00533
Mouse: Q01279
Rat: Q9WTS1
Monkey: P55245
Alternative Names ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2; epidermal growth factor receptor; EGFR vIII; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD47 & CLDN18 & EGFR Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR & ERBB3 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A289D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A289T) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A289V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A763, Y764insFHEA) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A763, Y764insFQEA) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A763, Y764insFQEA, C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d752-759) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (D761Y) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (D770, N771insG) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (D770, N771insGF) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (D770, N771insGT) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (D770, N771insNPG) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, S768I) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, T790M) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, T790M, C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, T790M, L798I) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, T790M, L858R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d747-749) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d747-749, A750P) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A763, Y764insFQEA, T790M) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (A767, S768insTLA) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (C797A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (C797S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, C797A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EGFR (d746-750, C797G) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: Ba/F3 Assay Types: Functional assay
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