mProX™ Human EGFR Stable Cell Line
[CAT#: S01YF-1123-KX140]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
EGFR
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research; Inflammation Research
Related Diseases
Inflammatory Skin And Bowel Disease; Lung Cancer
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
A transmembrane protein called the epidermal growth factor receptor (EGFR) binds to extracellular protein ligands that are members of the epidermal growth factor family (EGF family). The ErbB family of receptors, which consists of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3), and Her 4 (ErbB-4), includes the epidermal growth factor receptor. Mutations altering EGFR expression or activity have the potential to cause cancer in a variety of cancer types. In humans, over-expression of EGFR and other receptor tyrosine kinases is linked to the development of a wide range of malignancies, while deficient signaling is linked to disorders like Alzheimer's. The customized EGFR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
David
Recommended for all labs based on my experience of using this EGFR cell line.
May 23 2021
Verified Customer
Ashley
The EGFR KO cell line was an indispensable tool in my research. The cell line's stability and reproducibility were outstanding, allowing for reliable results across multiple experiments.
Sep 03 2021
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
