EDNRB
This gene encodes a G protein-coupled receptor protein that triggers a calcium-phosphatidylinositol second messenger pathway. Three highly effective vasoactive peptides make up its ligand, endothelin, including ET1, ET2, and ET3. The endothelinB receptor (ETB receptor) is a G-protein-coupled receptor that is a part of the endothelin receptor group, which also includes ETA. They are principally found in vascular endothelial cells, where they contribute to cell proliferation, vasoconstriction, and vasodilation.
Full Name | Endothelin receptor type B |
Gene ID | Human: 1910 Mouse: 13618 Rat: 50672 Monkey: 697329 |
UniProt ID | Human: P24530 Mouse: P48302 Rat: P21451 Monkey: Q28468 |
Alternative Names | ETB; ET-B; ETB1; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2; Hirschsprung disease 2; endothelin receptor non-selective type; endothelin receptor subtype B1; EDNRB; Endothelin receptor type B |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin Receptor Target Protein Species: Human Host Cell Type: HEK293T Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin receptor Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRB Target Family: Endothelin Family Target Protein Species: Human Host Cell Type: MDA-MB-231;BT549;CHO-K1;HEK293