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DRD4

The D4 subtype of the dopamine receptor is encoded by this gene. Adenylyl cyclase is inhibited by the G-protein coupled receptor of the D4 subtype. It is a target for medications that treat Parkinson's disease and schizophrenia. The attention deficit/hyperactivity disorder (ADHD), autonomic nervous system dysfunction, and the personality trait of novelty seeking have all been linked to mutations in this gene.

Full Name Dopamine receptor D4
Gene ID Human: 1815
Mouse: 13491
Rat: 25432
Monkey: 699697
UniProt ID Human: P21917
Mouse: P51436
Rat: P30729
Monkey: F7H4T0
Alternative Names D4DR; D(4) dopamine receptor; D(2C) dopamine receptor; dopamine D4 receptor; seven transmembrane helix receptor; DRD4; Dopamine receptor D4

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: DRD4 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: DRD4 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: DRD4 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: DRD4 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: DRD4 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: DRD4 Target Family: Dopamine Family Target Protein Species: Mouse Host Cell Type: RAW;264.7;CHO-K1;HEK293
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