DRD4
The D4 subtype of the dopamine receptor is encoded by this gene. Adenylyl cyclase is inhibited by the G-protein coupled receptor of the D4 subtype. It is a target for medications that treat Parkinson's disease and schizophrenia. The attention deficit/hyperactivity disorder (ADHD), autonomic nervous system dysfunction, and the personality trait of novelty seeking have all been linked to mutations in this gene.
| Full Name | Dopamine receptor D4 |
| Gene ID | Human: 1815 Mouse: 13491 Rat: 25432 Monkey: 699697 |
| UniProt ID | Human: P21917 Mouse: P51436 Rat: P30729 Monkey: F7H4T0 |
| Alternative Names | D4DR; D(4) dopamine receptor; D(2C) dopamine receptor; dopamine D4 receptor; seven transmembrane helix receptor; DRD4; Dopamine receptor D4 |
Product List
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Magic™ Human DRD4 (NM_000797) HEK293T Gαqi5 Membrane Preparation
[CAT#: S01YF-0722-KX599]
- Product Category:
- Membranes
- Target Protein: D4 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human DRD4 (NM_000797) HEK293T Membrane Preparation
[CAT#: S01YF-0722-KX598]
- Product Category:
- Membranes
- Target Protein: D4 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human DRD4 Cell Line with 14-3-3γ Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX156]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human DRD4 Chem-1 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX302]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Magic™ Human DRD4 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX224]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human DRD4 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-0822-KX317]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human DRD4 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX316]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human DRD4 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX111]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged DRD4 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX302]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged DRD4 HEK293T Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX303]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
Magic™ Rat DRD4 [35S]GTPγS binding Assay
[CAT#: S01YF-1122-KX413]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: DRD4 Target Family: Dopamine Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: [35S]GTPγS binding Assay
Magic™ Rat DRD4 Radioligand Binding Assay
[CAT#: S01YF-1122-KX414]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: DRD4 Target Family: Dopamine Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: Radioligand Binding Assay
mProX™ Human DRD4 Stable Cell Line
[CAT#: S01YF-0923-PY62]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD4 Target Family: Dopamine Family Target Protein Species: Mouse Host Cell Type: RAW;264.7;CHO-K1;HEK293 Assay Types: Biological assays
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