DRD3
The D3 subtype of the five (D1-D5) dopamine receptors is encoded by this gene. The G proteins that block adenylyl cyclase are the mediating factor in the activity of the D3 subtype receptor. The limbic regions of the brain, which are linked to cognitive, emotional, and endocrine activities, are where this receptor is found. Hereditary essential tremor susceptibility may be correlated with genetic variation in this gene.
Full Name | Dopamine receptor D3 |
Gene ID | Human: 1814 Mouse: 13490 Rat: 29238 Monkey: 100425047 |
UniProt ID | Human: P35462 Mouse: P30728 Rat: P19020 Monkey: P52703 |
Alternative Names | D3DR; ETM1; FET1; D(3) dopamine receptor; essential tremor 1; DRD3; Dopamine receptor D3 |
Product List
- Product Category:
- Membranes
- Target Protein: D3 Target Family: Dopamine Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membranes
- Target Protein: D3 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gqi5 Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: Dopamine Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
- Product Category:
- Membranes
- Target Protein: D3 Target Family: Dopamine Target Protein Species: Human Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: DPM Receptors Target Protein Species: Human Protein Tag: tGFP tag Host Cell Type: SH-SY5Y Assay Types: Internalization Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: Dopamine Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD3 Target Family: Dopamine Family Target Protein Species: Human Host Cell Type: HeLa;CHO-K1;HEK293 Assay Types: Biological assays