DDR2
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
| Full Name | discoidin domain receptor tyrosine kinase 2 |
| Gene ID | Human: 4921 Mouse: 18214 Rat: 685781 Monkey: 720124 |
| UniProt ID | Human: Q16832 Mouse: Q62371 Rat: B1WC09 |
| Alternative Names | TKT; WRCN; MIG20a; NTRKR3; TYRO10;discoidin domain-containing receptor 2;CD167 antigen-like family member B;cell migration-inducing protein 20;discoidin domain receptor 2;discoidin domain receptor family, member 2;discoidin domain-containing receptor tyrosine kinase 2;hydroxyaryl-protein kinase;migration-inducing gene 16 protein;neurotrophic tyrosine kinase receptor related 3;receptor protein-tyrosine kinase TKT;tyrosine-protein kinase TYRO10 |
Product List
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Magic™ Human DDR2 Assay
[CAT#: S01YF-1122-KX1101]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: DDR2 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human DDR2 Stable Cell Line
[CAT#: S01YF-1123-KX214]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DDR2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: MHCC-97H; CHO-K1; HEK293
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