DDR1
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Full Name | discoidin domain receptor tyrosine kinase 1 |
| Gene ID | Human: 780 Mouse: 12305 Rat: 25678 Monkey: 714233 |
| UniProt ID | Human: Q08345 Mouse: Q03146 Rat: Q63474 |
| Alternative Names | CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A;epithelial discoidin domain-containing receptor 1;CD167 antigen-like family member A;PTK3A protein tyrosine kinase 3A;cell adhesion kinase;mammary carcinoma kinase 10;neuroepithelial tyrosine kinase;neurotrophic tyrosine kinase, receptor, type 4;protein-tyrosine kinase RTK-6;tyrosine kinase DDR;tyrosine-protein kinase CAK |
Product List
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Human DDR1 Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX729]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
Human DDR1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX154]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human DDR1 Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1074]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
Human DDR1 Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX499]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
Human DDR1 Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX844]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
Human DDR1 Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX39]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme
Human DDR1 Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX269]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human DDR1 Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX384]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
Human DDR1 Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX959]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
Human DDR1 Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX614]
- Product Category:
- Membrane Protein Tools
- Target Protein: DDR1 Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
mProX™ Human DDR1 Stable Cell Line
[CAT#: S01YF-1123-KX213]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DDR1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: MCF7; CHO-K1; HEK293
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