CYSLTR1
A member of the G-protein coupled receptor 1 family is encoded by this gene. The encoded protein functions as a receptor for cysteinyl leukotrienes and is necessary for the activation of a second messenger system involving phosphatidylinositol and calcium, which mediates bronchoconstriction. When the encoded receptor is activated, bronchial smooth muscle cells contract and multiply, eosinophils migrate, and the mucus layer in the lung is harmed. Asthma is linked to the upregulation of this gene, and cancer may be linked to the dysregulation of this gene.
| Full Name | Cysteinyl leukotriene receptor 1 |
| Gene ID | Human: 10800 Mouse: 58861 Rat: 114099 Monkey: 706663 |
| UniProt ID | Human: Q9Y271 Mouse: Q99JA4 Rat: Q924T8 Monkey: F7AB41 |
| Alternative Names | CYSLT1; CYSLTR; CYSLT1R; HMTMF81; G-protein coupled receptor HG55; LTD4 receptor; cysteinyl leukotriene D4 receptor; CYSLTR1; Cysteinyl leukotriene receptor 1 |
Product List
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Magic™ Human FLAG tagged CYSLTR1 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX399]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CYSLTR1 Target Family: Leukotriene/Lipoxin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human CYSLTR1 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX69]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CYSLTR1 Target Family: Leukotriene receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human CYSLTR1 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX157]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CYSLTR1 Target Family: Leukotriene receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human CYSLTR1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX158]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CYSLTR1 Target Family: Leukotriene receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
mProX™ Human CYSLTR1 Stable Cell Line
[CAT#: S01YF-0923-PY94]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CYSLTR1 Target Family: Leukotriene Family Target Protein Species: Human Host Cell Type: SW480;HT-29;CHO-K1;HEK293
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