CXCR1
This gene encodes a protein that belongs to the family of G-protein-coupled receptors. This protein serves as the interleukin 8 receptor (IL8). It has a strong affinity for IL8 and transmits the signal using a second messenger pathway that is triggered by G proteins. This protein may prevent the migration of embryonic oligodendrocyte precursors in the developing spinal cord, according to mouse knockout experiments. Interleukin-8 receptor, a potent chemotactic factor for neutrophils. IL-8 binding to the receptor results in neutrophil activation. A G-protein that activates the phosphatidylinositol-calcium second messenger pathway mediates this reaction. This receptor has a low affinity for MGSA (GRO) and a high affinity for IL-8.
| Full Name | C-X-C motif chemokine receptor 1 |
| Gene ID | Human: 3577 Mouse: 227288 Rat: 54258 Monkey: 692074 |
| UniProt ID | Human: P25024 Mouse: Q810W6 Rat: P70612 Monkey: Q2YEG0 |
| Alternative Names | C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; IL-8 receptor type 1; IL-8R A; chemokine (C-X-C motif) receptor 1; high affinity interleukin-8 receptor A; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; CXCR1; C-X-C motif chemokine receptor 1 |
Product List
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Magic™ Human CXCR1 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX36]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR1 Target Family: Chemokine receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human CXCR1 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX29]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
mProX™ Human CXCR1 Stable Cell Line
[CAT#: S01YF-0923-PY44]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR1 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: Saos2;CHO-K1;HEK293
Magic™ Human FLAG tagged CXCR1 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX271]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged CXCR1 HEK293T Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX272]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
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