CX3CR1
Leukocyte adhesion and migration are aided by the transmembrane protein and chemokine known as fractalkine. This gene produces a protein that functions as a receptor for fractalkine. A few genetic polymorphisms in this gene increase susceptibility to HIV-1 infection and hasten the development of AIDS because the encoded protein serves as a coreceptor for HIV-1. Many early leukocyte cells have the C-X3-C chemokine fractalkine (CX3CL1) receptor, and this signaling pair is important for immune response, inflammation, cell adhesion, and chemotaxis in several organ compartments.
| Full Name | C-X3-C motif chemokine receptor 1 |
| Gene ID | Human: 1524 Mouse: 13051 Rat: 171056 Monkey: 693926 |
| UniProt ID | Human: P49238 Mouse: Q9Z0D9 Rat: P35411 Monkey: A0A2K5ERH4 |
| Alternative Names | V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1; CX3C chemokine receptor 1; C-X3-C CKR-1; CMK-BRL-1; CMK-BRL1; G-protein coupled receptor 13; beta chemokine receptor-like 1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; fractalkine receptor; CX3CR1; C-X3-C motif chemokine receptor 1 |
Product List
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Magic™ Human CX3CR1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX343]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human CX3CR1 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX344]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human CX3CR1 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX98]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Target Family: Chemokine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged CX3CR1 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX269]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged CX3CR1 HEK293T Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX270]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
Magic™ Knockout CX3CR1 THP-1 Cell Line
[CAT#: S01YF-1222-KX908]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Host Cell Type: THP-1
mProX™ Human CX3CR1 Stable Cell Line
[CAT#: S01YF-0923-PY43]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CX3CR1 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: GES-1;MKN-28;SGC-7901;MKN-45;CHO-K1;HEK293
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