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CSNK1A1

Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytosol; and nuclear speck. Part of beta-catenin destruction complex. Colocalizes with keratin filament and mRNA cleavage and polyadenylation specificity factor complex. Biomarker of Alzheimer's disease and inclusion body myositis.

Full Name casein kinase 1 alpha 1
Gene ID Human: 1452 Mouse: 93687 Rat: 113927 Monkey: 710775
UniProt ID Human: P48729 Mouse: Q8BK63 Rat: P97633
Alternative Names CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p;casein kinase I isoform alpha;CKI-alpha;clock regulator kinase;down-regulated in lung cancer;epididymis secretory sperm binding protein Li 77p

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CSNK1A1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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