mProX™ Human CSNK1A1 Stable Cell Line
[CAT#: S01YF-1123-KX195]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
CSNK1A1
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Digestive and Renal Research
Related Diseases
Enterobiasis and Amelogenesis Imperfecta, Type Iiia. Among its related pathways are CTNNB1 S45 mutants aren't phosphorylated and Regulation of activated PAK-2p34 by proteasome mediated degradation.
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
A member of the highly conserved serine/threonine protein kinase family is casein kinase 1, alpha 1 (CSNK1A1). There is expression of Csnk1a1 mRNA and protein in various mouse organs, including the ovary. Csnk1a1 mRNA and protein were found in preimplantation embryos following ovulation and fertilization, with two-cell stage embryos exhibiting the highest expression of both molecules. Preimplantation embryos' cytoplasm was likewise where the majority of the CSNK1A1 protein was found. Furthermore, the rate of blastocyst development was significantly reduced in zygotes upon Csnk1a1 knockdown. Moreover, embryonic developmental arrest was also induced by treating zygotes with the CSNK1A1-specific inhibitor D4476. These findings offer the first proof of CSNK1A1's unique role in the early stages of mouse embryonic development. The customized CSNK1A1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Kimberly
The CSNK1A1 KD cell line is easy to use and has become an essential tool in my lab.
Dec 06 2020
Verified Customer
Gary
The CSNK1A1 KD cell line allowed me to perform rigorous experiments with consistent results.
Jun 26 2022
Verified Customer
FAQ
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