CRHR1
The neuropeptides from the corticotropin-releasing hormone family, which are important regulators of the hypothalamic-pituitary-adrenal pathway, bind to the G-protein coupled receptor that this gene encodes. The encoded protein is necessary for the signal transduction pathways that control a variety of physiological processes, such as stress, reproduction, immunological response, and obesity, to be activated. Guanine nucleotide-binding proteins and downstream effectors, such as adenylate cyclase, are used to initiate signaling once ligand binding results in a conformation change. encourages adenylate cyclase activity, which raises intracellular cAMP levels. inhibits the calcium channel CACNA1H's activity. essential for the adrenal gland's healthy embryonic development as well as for healthy hormonal reactions to stress.
| Full Name | Corticotropin releasing hormone receptor 1 |
| Gene ID | Human: 1394 Mouse: 12921 Rat: 58959 Monkey: 574095 |
| UniProt ID | Human: P34998 Mouse: P35347 Rat: P35353 Monkey: Q76LL8 |
| Alternative Names | CRF1; CRHR; CRF-R; CRFR1; CRF-R1; CRFR-1; CRH-R1; CRHR1L; CRF-R-1; CRH-R-1; corticotropin-releasing factor type 1 receptor; seven transmembrane helix receptor; CRHR1; Corticotropin releasing hormone receptor 1 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: Corticotropin releasing factor receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: Corticotropin releasing factor receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: Corticotropin releasing factor receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: CRF Receptor Family Target Protein Species: Mouse Host Cell Type: bEnd3;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: Corticotrophin-Releasing Factor Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CRHR1 Target Family: Corticotrophin-Releasing Factor Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
