CLEC7A
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
| Full Name | C-type lectin domain containing 7A |
| Gene ID | Human: 64581 Mouse: 56644 Rat: 502902 Monkey: 574356 |
| UniProt ID | Human: Q9BXN2 Mouse: Q6QLQ4 Rat: B2RYG9 Monkey: Q8HZR8 |
| Alternative Names | CLEC7A; BGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12; C-type lectin domain family 7 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin superfamily member 12; DC-associated C-type lectin 1; beta-glucan receptor; dectin-1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; C-type lectin domain containing 7A |
Product List
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Magic™ Human Dectin-1a HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX376]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Dectin-1a Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human Dectin-1b HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX377]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Dectin-1b Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Mouse Dectin-1b HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX378]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Dectin-1b Target Family: Others Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
mProX™ Human CLEC7A Stable Cell Line
[CAT#: S01YF-1023-PY295]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;DCs
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