Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. CLEC7A
  3. mProX™ Human CLEC7A Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP Other Cell Lines,Drug Discovery Tools

    mProX™ Human CLEC7A Stable Cell Line

    [CAT#: S01YF-1023-PY295]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;DCs
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Infectious Research
    Related Diseases
    Aspergillosis; Candidiasis, Familial, 4
    Gene ID
    Human:64581
    UniProt ID
    Human:Q9BXN2

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CLEC7A, also known as C-type lectin domain family 7 member A, has various applications in different fields. In the context of lung adenocarcinoma, CLEC7A is one of the key genes regulating tumor infiltrating plasma cells (PC) and can be used to predict prognosis and treatment efficacy. It is also associated with shorter overall survival and can be used as a predictive marker. In the field of neuropathic pain, CLEC7A is involved in the activation of the Clec7a-MAPK/NF-κB-NLRP3 inflammasome axis, and its inhibition can ameliorate pain symptoms. In Parkinson's disease, CLEC7A is a therapeutic target for alleviating neuroinflammation. Additionally, CLEC7A is associated with disrupted epithelial permeability and the induction of inflammatory genes in the context of small intestinal absorptive cells. In severe COVID-19 cases, CLEC7A is one of the proteins that can predict disease progression and mortality. Overall, CLEC7A has implications in cancer prognosis, pain management, neurodegenerative diseases, intestinal health, and COVID-19 severity.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CLEC7A Stable Cell Line (S01YF-1023-PY295). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Casey Jones (Verified Customer)

    How does CLEC7A influence neuroinflammatory injury? Aug 20 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CLEC7A is involved in neuroinflammatory processes, as seen in neuropathic pain, where its axis may be targeted for relieving pain through alleviating neuroinflammation. Aug 20 2020

    chat Taylor Smith (Verified Customer)

    What role does CLEC7A play in immune responses? Jul 08 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CLEC7A expression in macrophages orchestrates the progression of acute kidney injury, indicating its crucial role in regulating macrophage phenotype during inflammatory responses. Jul 08 2023

    Related Products by Target
    • mProX™ Human CLEC7A Stable Cell Line (CAT#: S01YF-1023-PY295)
    • Magic™ Human Dectin-1b HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX377)
    • Magic™ Human Dectin-1a HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX376)
    • Magic™ Mouse Dectin-1b HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX378)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare