CLEC6A
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene.
| Full Name | C-type lectin domain containing 6A |
| Gene ID | Human: 93978 Monkey: 716162 |
| UniProt ID | Human: Q6EIG7 Mouse: Q9JKF4 Rat: D3ZWT9 Monkey: F6S605 |
| Alternative Names | CLEC4N; CLECSF10; dectin-2; hDECTIN-2; C-type lectin domain family 6 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; dendritic cell-associated C-type lectin 2 |
Product List
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Magic™ Mouse Dectin-2 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX379]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Dectin-2 Target Family: Others Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
mProX™ Human CLEC6A Stable Cell Line
[CAT#: S01YF-1023-PY296]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
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