CLDN6
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
| Full Name | Claudin 6 |
| Gene ID | Human: 9074 Mouse: 54419 Rat: 287098 Monkey: 102140361 |
| UniProt ID | Human: P56747 Mouse: Q9Z262 Rat: B4F7F0 Monkey: F7AWZ8 |
| Alternative Names | CLDN6; claudin-6; skullin; Claudin 6 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN6 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: B16F10 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN6 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN6 Target Family: Others Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN6 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN6 Target Family: Others Target Protein Species: Human Host Cell Type: LL/2 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN6 Target Family: Others Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MDA-MB-231
