CLDN6
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
Full Name | Claudin 6 |
Gene ID | Human: 9074 Mouse: 54419 Rat: 287098 Monkey: 102140361 |
UniProt ID | Human: P56747 Mouse: Q9Z262 Rat: B4F7F0 Monkey: F7AWZ8 |
Alternative Names | CLDN6; claudin-6; skullin; Claudin 6 |
Product List
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: CLDN6 Target Family: Others Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MDA-MB-231