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CHUK

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Full Name component of inhibitor of nuclear factor kappa B kinase complex
Gene ID Human: 1147 Mouse: 12675 Rat: 309361 Monkey: 709511
UniProt ID Human: O15111 Mouse: Q60680 Rat: B5DF32
Alternative Names BPS2; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha;inhibitor of nuclear factor kappa-B kinase subunit alpha;I-kappa-B kinase 1;I-kappa-B kinase-alpha;IKK-a kinase;IkB kinase alpha subunit;Nuclear factor NFkappaB inhibitor kinase alpha;TCF-16;conserved helix-loop-helix ubiquitous kinase;transcription factor 16

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHUK Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: H1437; CHO-K1; HEK293
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