mProX™ Human CHUK Stable Cell Line
[CAT#: S01YF-1123-KX263]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
CHUK
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
H1437; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Reproductive Research
Related Diseases
Fetal Encasement Syndrome and Bartsocas-Papas Syndrome 2. Among its related pathways are MyD88 dependent cascade initiated on endosome and TNFR1 Pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Nuclear factor inhibitor The CHUK gene in humans encodes kappa-B kinase subunit alpha (IKK-α), which is sometimes referred to as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK). The IκB kinase complex, which includes IKK-α, is crucial for controlling the NF-κB transcription factor. Nevertheless, IKK-α is believed to regulate epidermal differentiation independently of the NF-κB pathway and has numerous other cellular targets. The potential therapeutic benefit of inhibiting IκB kinase (IKK) and IKK-related kinases, such as IKBKE (IKKε) and TANK-binding kinase 1 (TBK1), has been explored for the management of cancer and inflammatory disorders. The customized CHUK stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
James
I've been using the mouse CHUK overexpression cell line for my studies.
May 19 2021
Verified Customer
Anthony
The CHUK overexpression cell line showed good performance in our hands.
Feb 20 2020
Verified Customer
FAQ
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