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CHRM4

A wider family of G protein-coupled receptors includes the muscarinic cholinergic receptors. The binding of acetylcholine defines the functional diversity of these receptors, which includes physiological reactions such adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Numerous cholinergic effects on the central and peripheral nervous systems are influenced by muscarinic receptors. Although the therapeutic relevance of this receptor is unknown, animal studies have connected its action to adenylyl cyclase inhibition.

Full Name Cholinergic receptor muscarinic 4
Gene ID Human: 1132
Mouse: 12672
Rat: 25111
Monkey: 574195
UniProt ID Human: P08173
Mouse: P32211
Rat: P08485
Monkey: A0A2K6S6M7
Alternative Names HM4; M4R; muscarinic acetylcholine receptor M4; acetylcholine receptor, muscarinic 4; CHRM4; Cholinergic receptor muscarinic 4

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Muscarinic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Muscarinic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: M4 Target Family: Acetylcholine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ mPro Rat CHRM4 Cell Line [CAT#: S01YF-1122-KX64]

Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Acetylcholine Receptors Target Protein Species: Rat
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CHRM4 Target Family: Muscarinic Acetylcholine Family Target Protein Species: Human Host Cell Type: PC3;CHO-K1;HEK293
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