CELSR1
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis.
| Full Name | Cadherin EGF LAG seven-pass G-type receptor 1 |
| Gene ID | Human: 9620 Mouse: 12614 Rat: 300128 Monkey: 718440 |
| UniProt ID | Human: Q9NYQ6 Mouse: O35161 Rat: F1MAS4 Monkey: F7HKR7 |
| Alternative Names | ME2; FMI2; CDHF9; HFMI2; ADGRC1; cadherin EGF LAG seven-pass G-type receptor 1; adhesion G protein-coupled receptor C1; cadherin family member 9; cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); flamingo homolog 2; protocadherin flamingo 2; CELSR1; Cadherin EGF LAG seven-pass G-type receptor 1 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CELSR1 Target Family: Cadherin Family Target Protein Species: Human Host Cell Type: K-562; CHO-K1; HEK293
