CDK9
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
| Full Name | cyclin dependent kinase 9 |
| Gene ID | Human: 1025 Mouse: 107951 Rat: 362110 Monkey: 699840 |
| UniProt ID | Human: P50750 Mouse: Q99J95 Rat: Q641Z4 |
| Alternative Names | TAK; C-2k; CTK1; CDC2L4; PITALRE;cyclin-dependent kinase 9;CDC2-related kinase;cell division cycle 2-like protein kinase 4;cell division protein kinase 9;serine/threonine protein kinase PITALRE;tat-associated kinase complex catalytic subunit |
Product List
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mProX™ Human CDK9 Stable Cell Line
[CAT#: S01YF-1123-KX191]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK9 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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