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  • mProX™ Human CDK9 Stable Cell Line

    [CAT#: S01YF-1123-KX191]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX1077 Magic™ Human CDK9/CycT1 in Vitro Assay Human Kinase Assay

    Product Information

    Target Protein
    CDK9
    Target Family
    Kinases/Enzyme Drug Discovery Assays and Products
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Kinase Cell Lines
    Target Research Area
    CNS Research; Cardiovascular Research; Auditory and Otology Research; Ocular Research; Reproductive Research
    Related Diseases
    Hypothyroidism, Congenital, Nongoitrous, 6 and Charge Syndrome. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and HIV Life Cycle
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    A cyclin-dependent kinase linked to P-TEFb is called cyclin-dependent kinase 9, or CDK9. This gene codes for a protein that is a member of the CDK (cyclin-dependent kinase) family. Members of the CDK family are well-known cell cycle regulators and bear a striking resemblance to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It was discovered that this kinase is a part of the multiprotein complex TAK/P-TEFb. Cyclin T or Cyclin K, this protein's regulatory subunit, forms a complex with it and controls it. It was discovered that the HIV-1 Tat protein interacted with both this protein and cyclin T, indicating that this protein may be involved in AIDS. It is also known that CDK9 participates in the differentiation of skeletal muscle and forms associations with other proteins. The customized CDK9 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Christopher

    The CDK9 KO cell line enable us to develop new insights into its role in disease pathology. Apr 29 2022

    chat Verified Customer

    chat Karen

    We have found this CDK9 KO cell line to be highly reliable and robust, producing consistent results. Mar 10 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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