CDK7
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
| Full Name | cyclin dependent kinase 7 |
| Gene ID | Human: 1022 Mouse: 12572 Rat: 171150 Monkey: 699871 |
| UniProt ID | Human: P50613 Mouse: Q03147 Rat: P51952 |
| Alternative Names | CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15;cyclin-dependent kinase 7;39 KDa protein kinase;CDK-activating kinase 1;TFIIH basal transcription factor complex kinase subunit;cell division protein kinase 7;cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase);homolog of Xenopus MO15 Cdk-activating kinase;kinase subunit of CAK;serine/threonine kinase stk1;serine/threonine protein kinase 1;serine/threonine protein kinase MO15 |
Product List
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Magic™ Human CDK7/CycH/MAT1 Assay
[CAT#: S01YF-1122-KX1075]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: CDK7/CycH/MAT1 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human CDK7 Stable Cell Line
[CAT#: S01YF-1123-KX189]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK7 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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