mProX™ Human CDK7 Stable Cell Line

[CAT#: S01YF-1123-KX189]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1075	Magic™ Human CDK7/CycH/MAT1 in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

CDK7

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Pigmentation Research

Related Diseases

Trichothiodystrophy and Xeroderma Pigmentosum, Variant Type. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and RNA Polymerase II Transcription Initiation And Promoter Clearance

Gene ID

1022

UniProt ID

P50613

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Humans have an enzyme called cyclin-dependent kinase 7, or cell division protein kinase 7. The CDK7 gene encodes this enzyme. This gene codes for a protein that belongs to the family of cyclin-dependent protein kinases, or CDKs. Members of the CDK family, who are known to be significant regulators of cell cycle progression, are very similar to the gene products of Saccharomyces cerevisiae cdc28 and Schizosaccharomyces pombe cdc2. Together with cyclin H and MAT1, this protein forms a trimeric complex that activates Cdk (CAK). It is a crucial part of the transcription factor TFIIH, which is involved in DNA repair and transcription initiation. It is believed that this protein acts as a direct conduit between the cell cycle and transcription control. The customized CDK7 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Patricia

Using the mouse CDK7 cell line from Creative Biolabs has been a game-changer for our research. Feb 09 2021

chat Verified Customer

chat Brian

It was instrumental in our study, allowing us to specifically target CDK7 proteins and investigate their role in disease. Dec 11 2021

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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