CDK12
Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex.
Full Name | cyclin dependent kinase 12 |
Gene ID | Human: 51755 Mouse: 69131 Rat: 192350 Monkey: 696733 |
UniProt ID | Human: Q9NYV4 Mouse: Q14AX6 Rat: Q3MJK5 |
Alternative Names | CRK7; CRKR; CRKRS;cyclin-dependent kinase 12;CDC2-related protein kinase 7;Cdc2-related kinase, arginine/serine-rich;cell division cycle 2-related protein kinase 7;cell division protein kinase 12 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK12 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HCT116; CHO-K1; HEK293