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CDK12

Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex.

Full Name cyclin dependent kinase 12
Gene ID Human: 51755 Mouse: 69131 Rat: 192350 Monkey: 696733
UniProt ID Human: Q9NYV4 Mouse: Q14AX6 Rat: Q3MJK5
Alternative Names CRK7; CRKR; CRKRS;cyclin-dependent kinase 12;CDC2-related protein kinase 7;Cdc2-related kinase, arginine/serine-rich;cell division cycle 2-related protein kinase 7;cell division protein kinase 12

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CDK12 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HCT116; CHO-K1; HEK293
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