CDC42BPA
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described
Full Name | CDC42 binding protein kinase alpha |
Gene ID | Human: 8476 Mouse: 226751 Rat: 114116 Monkey: 697811 |
UniProt ID | Human: Q5VT25 Mouse: Q3UU96 Rat: O54874 |
Alternative Names | MRCK; MRCKA; PK428;serine/threonine-protein kinase MRCK alpha;CDC42 binding protein kinase alpha (DMPK-like);CDC42 binding protein kinase beta;myotonic dystrophy kinase-related CDC42-binding protein kinase alpha;myotonic dystrophy protein kinase-like alpha;ser-thr protein kinase PK428;ser-thr protein kinase related to the myotonic dystrophy protein kinase |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HCT116;RKO