CD86
A type I membrane protein that belongs to the immunoglobulin superfamily is produced by this gene. This protein, which is produced by antigen-presenting cells, binds to the CD28 antigen and the cytotoxic T-lymphocyte-associated protein 4 on the surface of T cells. This protein's binding to the CD28 antigen serves as a costimulatory signal to activate T cells. When this protein and cytotoxic T-lymphocyte-associated protein 4 bind together, T-cell activation is negatively regulated, which reduces the immunological response.
| Full Name | CD86 molecule |
| Gene ID | Human: 942 Mouse: 12524 Rat: 56822 Monkey: 714390 |
| UniProt ID | Human: P42081 Mouse: P42082 Rat: O35531 Monkey: F6R7U3 |
| Alternative Names | CD86; B70; B7-2; B7.2; LAB72; CD28LG2; T-lymphocyte activation antigen CD86; B-lymphocyte activation antigen B7-2; BU63; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1; CD86 molecule |
Product List
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Magic™ Human CD274 & CD86 CT26 Cell Line
[CAT#: S01YF-0324-KX63]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD274 & CD86 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
Magic™ Human CD86 & CD274 MC-38 Cell Line
[CAT#: S01YF-0324-KX126]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD86 & CD274 Target Family: CD Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD86 CT26 Cell Line
[CAT#: S01YF-0324-KX47]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD86 Target Family: CD Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
Magic™ Human CD86 HEK293T Cell Line
[CAT#: S01YF-0123-KX331]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD86 Target Family: CD Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CD86 MC-38 Cell Line
[CAT#: S01YF-0324-KX105]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD86 Target Family: CD Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD86 U2OS Cell Line, Drug screening assay
[CAT#: S01YF-0822-KX226]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD86 Target Family: IgSF (immune inhibitory receptor ligand) Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Drug screening assay
mProX™ Human CD86 Stable Cell Line
[CAT#: S01YF-1023-PY223]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: CD Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;RPMI-8226;MM1.S Assay Types: Biological assays
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