CD38
Cyclic adenosine 5'-diphosphate-ribose, an intracellular messenger that mobilizes calcium ions, is synthesized and hydrolyzed by the type II transmembrane glycoprotein that this gene encodes. The protein appears to have both external and intracellular roles, as evidenced by the release of soluble protein and the capacity of membrane-bound protein to be internalized. This protein has a single membrane-spanning domain, an N-terminal cytoplasmic tail, a C-terminal extracellular region, and four N-glycosylation sites. Crystallographic study shows that the functional molecule is a dimer, with the catalytic site located in the middle. For people with chronic lymphocytic leukemia, it serves as a prognostic indicator.
Full Name | CD38 molecule |
Gene ID | Human: 952 Mouse: 12494 Rat: 25668 Monkey: 102126394 |
UniProt ID | Human: P28907 Mouse: P56528 Rat: Q64244 Monkey: Q5VAN0 |
Alternative Names | CD38; ADPRC1; ADPRC 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; CD38 antigen (p45); NAD(+) nucleosidase; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; CD38 molecule |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD38 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD38 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: E.G7-OVA Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD38 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: EL4 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD38 Target Family: Immune Checkpoint Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;H9C2