CD276
This gene encodes a protein that is a member of the immunoglobulin superfamily and is hypothesized to be involved in the control of the T-cell-mediated immunological response. Studies have shown that whereas this gene's transcript is universally expressed in both solid tumors and normal tissues, its protein is only preferentially expressed in tumor tissues. Furthermore, it was discovered that this transcript's 3' UTR has a target site for the microRNA miR29, and that there is an inverse relationship between the production of this protein and miR29 levels, indicating that miR29 may be regulating the expression of this gene product.
Full Name | CD276 molecule |
Gene ID | Human: 80381 Mouse: 102657 Rat: 315716 Monkey: 699877 |
UniProt ID | Human: Q5ZPR3 Mouse: Q8VE98 Rat: Q7TPB4 Monkey: F7G5V3 |
Alternative Names | CD276; B7H3; B7-H3; B7RP-2; 4Ig-B7-H3; CD276 antigen; B7 homolog 3; costimulatory molecule; CD276 molecule |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B7-H3 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & CD276 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD276 Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SCC1;SCC23;HN6