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CD276

This gene encodes a protein that is a member of the immunoglobulin superfamily and is hypothesized to be involved in the control of the T-cell-mediated immunological response. Studies have shown that whereas this gene's transcript is universally expressed in both solid tumors and normal tissues, its protein is only preferentially expressed in tumor tissues. Furthermore, it was discovered that this transcript's 3' UTR has a target site for the microRNA miR29, and that there is an inverse relationship between the production of this protein and miR29 levels, indicating that miR29 may be regulating the expression of this gene product.

Full Name CD276 molecule
Gene ID Human: 80381
Mouse: 102657
Rat: 315716
Monkey: 699877
UniProt ID Human: Q5ZPR3
Mouse: Q8VE98
Rat: Q7TPB4
Monkey: F7G5V3
Alternative Names CD276; B7H3; B7-H3; B7RP-2; 4Ig-B7-H3; CD276 antigen; B7 homolog 3; costimulatory molecule; CD276 molecule

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: B7-H3 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay
Magic™ Human CD276 CT26 Cell Line [CAT#: S01YF-0123-KX209]

Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD276 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD47 & CLDN18 & CD276 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CD276 Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SCC1;SCC23;HN6
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