CD14
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.
| Full Name | CD14 molecule |
| Gene ID | Human: 929 Mouse: 12475 Rat: 60350 Monkey: 697482 |
| UniProt ID | Human: P08571 Mouse: P10810 Rat: Q63691 Monkey: B3Y6B8 |
| Alternative Names | CD14; CD14 molecule; monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein |
Product List
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Magic™ Human CD14 & MD2 HEK293 Cell Line
[CAT#: S01YF-0123-KX414]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 Target Family: CD Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human CD14 & MD2 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX393]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 Target Family: CD Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human CD14 & MD2 THP-1 KO-TLR4 Cell Line with Luc & SEAP Reporter
[CAT#: S01YF-0123-KX480]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 Target Family: CD Target Protein Species: Human Host Cell Type: THP-1 KO-TLR4 Assay Types: Drug screening and biological assays
mProX™ Human CD14 Stable Cell Line
[CAT#: S01YF-1023-PY232]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: CD Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MGC-803
Magic™ Human CD14 & MD2 & TLR4 THP-1 Cell Line with Luc & SEAP Reporter
[CAT#: S01YF-0123-KX479]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 & TLR4 Target Family: CD Target Protein Species: Human Host Cell Type: THP-1 Assay Types: Drug screening and biological assays
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