CD14
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.
| Full Name | CD14 molecule |
| Gene ID | Human: 929 Mouse: 12475 Rat: 60350 Monkey: 697482 |
| UniProt ID | Human: P08571 Mouse: P10810 Rat: Q63691 Monkey: B3Y6B8 |
| Alternative Names | CD14; CD14 molecule; monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein |
Product List
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Magic™ Human CD14 & MD2 & TLR4 THP-1 Cell Line with Luc & SEAP Reporter
[CAT#: S01YF-0123-KX479]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 & TLR4 Target Family: CD Target Protein Species: Human Host Cell Type: THP-1 Assay Types: Drug screening and biological assays
Magic™ Human CD14 & MD2 HEK293 Cell Line
[CAT#: S01YF-0123-KX414]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 Target Family: CD Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human CD14 & MD2 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX393]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 Target Family: CD Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human CD14 & MD2 THP-1 KO-TLR4 Cell Line with Luc & SEAP Reporter
[CAT#: S01YF-0123-KX480]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD14 & MD2 Target Family: CD Target Protein Species: Human Host Cell Type: THP-1 KO-TLR4 Assay Types: Drug screening and biological assays
mProX™ Human CD14 Stable Cell Line
[CAT#: S01YF-1023-PY232]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: CD Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MGC-803
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Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
