CCR8

The beta chemokine receptor protein that this gene produces is projected to be a seven transmembrane protein, much like G protein-coupled receptors. The migration of different cell types into the inflammatory areas depends on chemokines and their receptors. The thymus is where this receptor protein expresses itself most frequently. This receptor's ligands include I-309, thymus activation-regulated cytokine (TARC), and macrophage inflammatory protein-1 beta (MIP-1 beta). Studies on this receptor and its ligands suggested that they may control the apoptosis of thymic cells and monocyte chemotaxis. More specifically, this receptor may help activated T lymphocytes locate correctly within antigenic challenge sites and targeted regions of lymphoid organs.

Full Name	C-C motif chemokine receptor 8
Gene ID	Human: 1237 Mouse: 12776 Rat: 301066 Monkey: 693806
UniProt ID	Human: P51685 Mouse: P56484 Rat: D4ADE0 Monkey: O97665
Alternative Names	CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; C-C chemokine receptor type 8; CC chemokine receptor 8; CC chemokine receptor CHEMR1; CC-chemokine receptor chemr1; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CCR8; C-C motif chemokine receptor 8

Product List

mProX™ Human CCR8 Stable Cell Line [CAT#: S01YF-0923-PY41]

Product Category:: Membrane Protein Stable Cell Lines

Datasheet

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