CCR8
The beta chemokine receptor protein that this gene produces is projected to be a seven transmembrane protein, much like G protein-coupled receptors. The migration of different cell types into the inflammatory areas depends on chemokines and their receptors. The thymus is where this receptor protein expresses itself most frequently. This receptor's ligands include I-309, thymus activation-regulated cytokine (TARC), and macrophage inflammatory protein-1 beta (MIP-1 beta). Studies on this receptor and its ligands suggested that they may control the apoptosis of thymic cells and monocyte chemotaxis. More specifically, this receptor may help activated T lymphocytes locate correctly within antigenic challenge sites and targeted regions of lymphoid organs.
| Full Name | C-C motif chemokine receptor 8 |
| Gene ID | Human: 1237 Mouse: 12776 Rat: 301066 Monkey: 693806 |
| UniProt ID | Human: P51685 Mouse: P56484 Rat: D4ADE0 Monkey: O97665 |
| Alternative Names | CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; C-C chemokine receptor type 8; CC chemokine receptor 8; CC chemokine receptor CHEMR1; CC-chemokine receptor chemr1; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CCR8; C-C motif chemokine receptor 8 |
Product List
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Magic™ Cyno CCR8 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX73]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CCR8 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX214]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Cyno CCR8 HEK293T Cell Line
[CAT#: S01YF-0123-KX149]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CCR8 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX187]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Dog CCR8 (HA) HEK293T Cell Line
[CAT#: S01YF-0123-KX23]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 (HA) Target Family: Chemokine Receptors Target Protein Species: Dog Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human FLAG tagged CCR8 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX256]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged CCR8 HEK293T Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX257]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
Magic™ Human CCR8 (NM_005201.2) HEK293T Gαqi5 Membrane Preparation
[CAT#: S01YF-0722-KX553]
- Product Category:
- Membranes
- Target Protein: CCR8 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human CCR8 (NM_005201.2) HEK293T Membrane Preparation
[CAT#: S01YF-0722-KX552]
- Product Category:
- Membranes
- Target Protein: CCR8 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human CCR8 (U45983) Chem-1 Membrane Preparation
[CAT#: S01YF-0722-KX966]
- Product Category:
- Membranes
- Target Protein: CCR8 Target Family: Chemokine Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human CCR8 Chem-1 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX215]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Magic™ Human CCR8 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX153]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CCR8 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX206]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human CCR8 CHO-S Cell Line
[CAT#: S01YF-0424-KX4]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay
Magic™ Human CCR8 HEK293 Cell Line with cAMP-biosensor Reporter
[CAT#: S01YF-1222-KX873]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human CCR8 HEK293T Cell Line
[CAT#: S01YF-0123-KX146]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CCR8 MC38 Cell Line
[CAT#: S01YF-0123-KX19]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC38 Assay Types: Drug screening and biological assays
Magic™ Mouse CCR8 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX97]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Mouse CCR8 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX616]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine receptor Target Protein Species: Mouse Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Mouse CCR8 HEK293T Cell Line
[CAT#: S01YF-0123-KX95]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Rabbit CCR8 (HA) HEK293T Cell Line
[CAT#: S01YF-0123-KX25]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 (HA) Target Family: Chemokine Receptors Target Protein Species: Rabbit Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Rat CCR8 HEK293T Cell Line
[CAT#: S01YF-0123-KX48]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Receptors Target Protein Species: Rat Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human CCR8 Stable Cell Line
[CAT#: S01YF-0923-PY41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR8 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: 5637;CHO-K1;HEK293 Assay Types: Biological assays
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