CCKBR
A G-protein coupled receptor for the regulating peptides gastrin and cholecystokinin (CCK), found in the brain and gastrointestinal system, is encoded by this gene. This protein is a type B gastrin receptor that is mostly located in the central nervous system and the gastrointestinal tract. It has a strong affinity for both sulfated and nonsulfated CCK analogs. There are several transcript variations as a result of alternative splicing. The central nervous system is home to CCK-B receptors, which regulate neuroleptic, analgesic, arousal, and anxiety-related activity. By collaborating with G proteins, which turn on the phosphatidylinositol-calcium second messenger system, this receptor exerts its effect.
| Full Name | Cholecystokinin B receptor |
| Gene ID | Human: 887 Mouse: 12426 Rat: 25706 Monkey: 712939 |
| UniProt ID | Human: P32239 Mouse: P56481 Rat: P30553 Monkey: F6YJW9 |
| Alternative Names | GASR; CCK-B; CCK2R; gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK2 receptor; cholecystokinin-2 receptor; gastrin receptor; CCKBR; Cholecystokinin B receptor |
Product List
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Magic™ Human CCKBR 1321N1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX156]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin receptor Target Protein Species: Human Host Cell Type: 1321N1 Assay Types: Calcium flux assay
Magic™ Human CCKBR 1321N1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX155]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin receptor Target Protein Species: Human Host Cell Type: 1321N1 Assay Types: Binding and Functional Assay
Magic™ Human CCKBR CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human CCKBR HEK293T Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX44]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin receptor Target Protein Species: Human Host Cell Type: HEK293T Assay Types: Reporter Assay
Magic™ Human CCKBR U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX64]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged CCKBR HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX289]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ mPro Human CCKBR Cell Line
[CAT#: S01YF-1122-KX17]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin Receptors Target Protein Species: Human
mProX™ Human CCKBR Stable Cell Line
[CAT#: S01YF-0923-PY56]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKBR Target Family: Cholecystokinin Family Target Protein Species: Human Host Cell Type: MCF-7;T47D;CHO-K1;HEK293
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