CAMKK2
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.
| Full Name | calcium/calmodulin dependent protein kinase kinase 2 |
| Gene ID | Human: 10645 Mouse: 207565 Rat: 83506 Monkey: 699685 |
| UniProt ID | Human: Q96RR4 Mouse: Q8C078 Rat: O88831 |
| Alternative Names | CAMKK; CAMKKB;calcium/calmodulin-dependent protein kinase kinase 2;CAMKK beta protein;caM-KK 2;caM-KK beta;caM-kinase kinase 2;caM-kinase kinase beta;calcium/calmodulin-dependent protein kinase beta;calcium/calmodulin-dependent protein kinase kinase 2, beta |
Product List
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- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: CAMKK2 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CAMKK2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
